Back in the early 2000's our base flew 1000+ flights per year, about 75% of those flights were scene calls. I flew between 325-360 flight hours year after year after year. If we weren't getting 100-120 flights per month during the busy trauma season, then we would wonder what the problem was. We never turned down flights for crew fatigue, we just went when called and napped in between flights. There were multiple shifts where we flew 5-6 patients in a 12 hour shift.